• J Res Med Sci · Jun 2014

    Detection of quinolone-resistance mutations of parC gene in clinical isolates of Acinetobacter baumannii in Iran.

    • Bahareh Vakili, Farzin Khorvash, Hossein Fazeli, and Moj Khaleghi.
    • Department of Microbiology, Science and Research Branch, Islami Azad University, Kerman, Iran.
    • J Res Med Sci. 2014 Jun 1; 19 (6): 567-70.

    BackgroundThe purpose of this study was to screen of parC gene mutations in clinical isolates of Acinetobacter baumannii from intensive care units (ICUs) of Alzahra Hospital, Isfahan, Iran.Materials And MethodsSeventy isolates of A. baumannii between March 2011 and June 2012 were studied. Susceptibility test was established by E-test method. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and sequencing was performed for detection of parC gene mutation.Results77.1% of specimens were highly resistant. Mutation at position 80 in parC was observed in 93% of isolates.ConclusionHigh proportion of A. baumannii isolates had a mutation in parC that can play an important role in increased incidence of these isolates.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…