• Anokha Oomman and Richard Goodwin.
• Core Surgical trainee, University Hospital of Wales, Cardiff, UK.
• J Res Med Sci. 2014 Jun 1; 19 (6): 577-9.

AbstractToxic epidermal necrolysis (TEN) is a rare, but life-threatening medical emergency with significant morbidity and mortality. Current treatment standards for TEN patients include stopping all possible drugs associated with the new onset of symptoms, prompt referral and treatment in a specialized center with fluid resuscitation, adequate analgesia and maintenance of nutritional needs. Extensive debridement of the involved epidermis followed by coverage with a skin substitute reduces the mortality from a skin infection and also improves the fluid and electrolyte balance and pain control. This is increasingly considered an important part of the intensive care of these patients. Admitting physicians should be aware of this rare but life-threatening emergency, to allow prompt diagnosis and avoid delays in treatment.

2 keywords...

hide…