• Raziye Keskin Kurt, Aycan KayaOzlemO, Atilla Karateke, Dilek Benk Silfeler, Oya Soylu Karapınar, Ayse Neslin Akkoca, and Ali Ulvi Hakverdi.
• Department of Obstetrics and Gynecology, Mustafa Kemal University Medical School, Hatay, Turkey.
• Med Princ Pract. 2014 Jan 1; 23 (4): 369-72.

ObjectiveTo investigate the presence of Demodex in patients with gestational diabetes and the impact of glucose regulation on Demodex density in gestational diabetes.Subjects And MethodsThe study population consisted of 33 patients with gestational diabetes and 30 pregnant women without gestational diabetes (control group). The age, parity, gestational age, and BMI of the study group were recorded and the patients were divided into 2 groups, i.e. those with regulated and unregulated glucose levels, according to their postprandial 1st- and 2nd-hour glucose values. A standardized skin surface biopsy method was used to determine if patients had Demodex folliculorum infestation (>5 mites/cm(2) of skin).ResultsPatients with gestational diabetes had a statistically significantly higher Demodex density compared to the control group (24.2 vs. 3.3%; p < 0.001). Furthermore, a significantly higher proportion of gestational diabetes patients with unregulated glucose levels had a higher Demodex density compared to those in the regulated subgroup (6/19 vs. 2/14; p = 0.001).ConclusionOur study revealed that the Demodex density was increased in gestational diabetes patients. Further, poor glucose regulation could be the mechanism responsible for the increased Demodex density in gestational diabetes patients with unregulated glucose levels compared to those with regulated glucose levels.© 2014 S. Karger AG, Basel.

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