• Mansur Doğan, Derya Ozdemir Doğan, Cevdet Düger, Ozdemir KolIclalI, Aysun Akpınar, Burcu Mutaf, and Türker Akar.
• Department of Otolaryngology, Cumhuriyet University School of Medicine, Sivas, Turkey.
• Med Princ Pract. 2014 Jan 1; 23 (6): 507-10.

ObjectiveIt was the aim of this study to compare the efficacy of ozone therapy and drug treatment in patients with painful temporomandibular joint (TMJ) disorder (TMD).Subjects And MethodsA total of 63 patients with TMD were enrolled; 33 were treated with bio-oxidative therapy and 30 with a ketoprofen tablet thiocolchicoside capsule 2 × 1 for 7 days. Maximum voluntary interincisal mouth opening (MMO) was measured in millimeters using a scale and recorded during the pre- and posttreatment periods. The patients evaluated their subjective pain using a visual analogue scale (VAS). Data were analyzed using the Mann-Whitney U test, the Kolmogorov-Smirnov test, and the independent t test.ResultsThe mean MMO of the group that received ozone therapy during the pretreatment period was 46.51 ± 8.2 mm, and it immediately increased to 48.78 ± 7.5 mm after 1 week of ozone therapy, which was statistically significant (p = 0.04). For those who received medication, the mean MMO during the pretreatment period was 46.30 mm, and at the end of 1 week it was 46.9 mm. In the ozone group, 29% of patients showed a gradual decrease in their VAS pain scores compared to pretreatment values (6.3 ± 2.1 to 3.0 ± 2.2). In the medication group, 24% of patients showed a significant decrease in VAS pain scores during the follow-up period (6.9 ± 1.4 to 5.0 ± 1.5).ConclusionThis study showed that bio-oxidative therapy was a more effective treatment than medication therapy for relieving TMJ pain.© 2014 S. Karger AG, Basel.

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