• B Bohnhorst, J F Kuebler, G Rau, S Gluer, B Ure, and M Doerdelmann.
• Hannover Medical School, Department of Pediatric Pulmonology, Allergology and Neonatology, Hannover, Germany. bohnhorst.bettina@mh-hannover.de
• Eur J Pediatr Surg. 2011 Jan 1; 21 (1): 12-7.

BackgroundThe definite clinical diagnosis of acquired neonatal intestinal diseases (ANID) is a challenge, usually met by applying Bell's or, more recently, Gordon's classification. Both classifications incorporate radiological pneumatosis intestinalis (PI) as a cornerstone of the NEC diagnosis. However, PI may be absent or difficult to identify by abdominal X-ray. Portal venous gas detected by ultrasound (PVG-US) has been proposed as another characteristic of NEC, but its incidence in other entities of ANID remains unknown.ObjectiveTo determine whether PVG-US and Gordon's classification can help to differentiate between NEC and other ANID, especially SIP.MethodsRetrospective analysis of the data of 83 infants, who underwent laparotomy for a clinical diagnosis of ANID was performed. The results of PVG-US and other markers of ANID were compared with the operative result, defined as the gold standard for diagnosis.ResultsThe NEC diagnosis was confirmed in 28/83 infants and PVG-US was present in 23 (82%) of those patients prior to operation. PVG-US was detected in 2 patients without NEC (one volvulus, one SIP), resulting in an 82% sensitivity and a 96% specificity. The sensitivity and specificity of radiological PI for patients with NEC was lower (75 and 91%), but the combination of PVG-US and radiological PI increased the sensitivity for NEC detection to 89%. Gordon's classification had a sensitivity of 93% and a specificity of 92% for NEC diagnosis.ConclusionScreening for PVG-US and Gordon's classification are valid tools to differentiate between NEC and other ANID including SIP. Although an effect of these proposed diagnostic tools on treatment regimen and operative management has yet to be verified, the improvement in diagnosing ANID is certainly valuable.© Georg Thieme Verlag KG Stuttgart · New York.

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