• Arzu Acar, Elvan Erhan, Nuri DenizMM, and Gulden Ugur.
• Department of Anaesthesiology and Reanimation, School of Medicine, Ege University, Izmir, Turkey.
• Anesth Pain Med. 2013 Jan 1; 2 (3): 119-22.

BackgroundTo alleviate stinging pain in the skin entry area and visceral discomfort in patients who are undergoing ESWL.ObjectivesThis study was designed to investigate the effectiveness of the EMLA cream in combination with remifentanil patient-controlled analgesia (PCA) in patients undergoing ESWL treatment.Patients And MethodsSixty patients were divided into two double-blind randomized groups. Those in the first group were administered 3-5mm of EMLA 5% cream on a marked area; the second group received, as a placebo, a cream with no analgesic effect in the same amount. All patients were administered a remifentanil bolus with a PCA device. Arterial blood pressure, oxygen saturation, and respiratory rate were recorded throughout the procedure; postoperative side effects, agitation, and respiratory depression were measured after. Visual Analogue Scale (VAS) scores were taken preoperatively, perioperatively, directly postoperatively, and 60 minutes subsequent to finishing the procedure.ResultsThere were no statistically significant differences in the frequency of PCA demands and delivered boluses or among perioperative VAS. No significant side effects were noted. Patient satisfaction was recorded high in both groups.ConclusionsEMLA cream offered no advantage over the placebo cream in patients undergoing ESWL with remifentanil PCA.

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