• Brain research · Apr 1999

    Clinical Trial

    Mapping of secondary somatosensory cortex activation induced by vibrational stimulation: an fMRI study.

    • J A Maldjian, A Gottschalk, R S Patel, D Pincus, J A Detre, and D C Alsop.
    • Department of Radiology, Ground Floor Founders, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA. maldjian@oasis.rad.upenn.edu
    • Brain Res. 1999 Apr 10; 824 (2): 291-5.

    AbstractSensory functional MRI was performed in seven normal volunteers at 1. 5 T using a vibratory stimulus applied to the pad of the first finger of the left hand. The data was normalized to a standard atlas, and individual and group statistical parametric maps were computed. Robust bilateral activation was demonstrated in the secondary somatosensory cortex (SII), indicating a bilateral representation of SII in humans. Greater maxima and activation volumes were achieved in contralateral SII as compared to SI. Sensory fMRI can provide a sensitive assay for probing the nature and function of SII in vivo.Copyright 1999 Elsevier Science B.V.

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