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- J R Bogner.
- Sektion Klinische Infektiologie, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Pettenkoferstr. 8a, 80336, München, Deutschland, jbogner@med.lmu.de.
- Internist (Berl). 2014 Dec 1; 55 (12): 1486-8, 1490-1.
BackgroundTherapeutic efficacy and safety in infections due to multiresistant bacteria can be improved by the clinical development of new compounds and devising new derivatives of already useful antibiotics. Due to a striking global increase of multiresistant gram-negative and gram-positive organisms, new antibiotics are urgently needed. This paper provides a review of new pharmaceuticals which are already in clinical development, mainly in phase III trials.ConclusionEach of these new trials increases the possibility of new antibiotics receiving approval.
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