• Int. J. Cardiol. · Oct 2021

    Case Reports

    Fulminant myocarditis and systemic hyperinflammation temporally associated with BNT162b2 mRNA COVID-19 vaccination in two patients.

    • Antonio Abbate, Josh Gavin, Nima Madanchi, Christin Kim, Pranav R Shah, Katherine Klein, Julie Boatman, Charlotte Roberts, Seema Patel, and Stamatina Danielides.
    • Division of Cardiology, Virginia Commonwealth University, Richmond, VA, United States of America. Electronic address: Antonio.abbate@vcuhealth.org.
    • Int. J. Cardiol. 2021 Oct 1; 340: 119-121.

    AbstractImmune-mediated myocardial injury following Severe Acute Respiratory Syndrome Coronavirys-2 (SARS-CoV2) infection has been described in adults and children. Cases of myocarditis following immunization for SARS-CoV2 have recently been documented, mostly associated with mild severity and spontaneous recovery. We herein report two cases of fulminant myocarditis following BNT162b2 mRNA Covid-19 vaccination associated with systemic hyperinflammatory syndrome and refractory shock requiring support with veno-arterial extracorporeal membrane oxygenation.Copyright © 2021 Elsevier B.V. All rights reserved.

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