• Clin J Pain · Nov 2013

    Case Reports

    Favorable Outcome of an Acute Complex Regional Pain Syndrome With Immunoglobulin Infusions.

    • Friedrich Medlin, Anastasia Zekeridou, and Susanne Renaud.
    • Nerve-Muscle Unit, Department of Clinical Neurosciences, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.
    • Clin J Pain. 2013 Nov 1;29(11):e33-4.

    ObjectiveTo emphasize that complex regional pain syndrome (CRPS), a disabling disorder with the implication of aberrant inflammation, vasomotor dysfunction, and maladaptive neuroplasticity, might be treated with a high dose of intravenous immunoglobulin infusions (IVIG).MethodsWe describe a patient who presented with CRPS in the acute phase of the disease.ResultsThe CRPS developed secondary to sciatic compression in a young patient and was treated within 10 days by high-dose IVIG (2 g/kg). It resolved completely within days after infusions.DiscussionThis observational study emphasizes that high-dose IVIG may be a treatment option in the acute phase of CRPS.

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