• Patricia Bofí Martínez, Emilio García Jiménez, and Martínez MartínezFernandoFDoctor en Farmacia, Responsable del Grupo de Investigación enAtención Farmacéutica, Universidad de Granada, Granada, España..
• Licenciada en Farmacia, Farmacéutica comunitaria, Farmacia de la Playa de Miramar, Valencia, España. Electronic address: mabopy@hotmail.com.
• Aten Primaria. 2015 Mar 1; 47 (3): 141148141-8.

AimTo compare health education (HE) and drug therapy monitoring (DTM) interventions in patients with cardiovascular risk factors (CVRF).DesignRandomised experimental studys: 100 patients per group.SettingPlaya-Miramar pharmacy (Valencia, Spain). March 2010-November 2011.ParticipantsPatients with one or more CVRF detected based on medication they were taking or questions they asked when drugs were dispensed. Patients were assigned to one of the two groups (HE or DTM) using a random number table. 100 patients by group were included.InterventionsSix months of DTM (DTMG) or health education (HEG) per patient.Main MeasurementsThe primary variables were modifiable CVRF: hypertension, dyslipidaemia, diabetes, smoking, obesity and low physical activity. Secondary variables were non modifiable CVRF (age, sex, cardiovascular disease), heart rate, body mass index, waist measurement, waist-to-hip ratio, waist-to-height ratio, body fat, treatment compliance.ResultsThe differences in the reduction percentages were statistically greater in DTMG than in HEG for the following variables: systolic pressure 5.40% (p=0.001); heart rate 2.95%(p=0.015); weight 2.00% (p=0.002); BMI 2.24% (p=0.003); fasting glucose 8.65% (p=0.004); total cholesterol 6.45% (p=0.002); waist measurement 1.85% (p=0.010); and waist-to-height ratio 1.66% (p=0.002). Triglycerides and body fat were reduced by 12.78% (p<0.001) and 1.84% (p<0.001) more, respectively, in DTMG. These differences were not statistically significant.ConclusionsThe reduction percentages were generally higher for all variables in DTMG except diastolic blood pressure, which decreased by 4.7% (P<.001) more in HEG because the baseline values were higher.Copyright © 2013 Elsevier España, S.L.U. All rights reserved.

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