• Atencion primaria · Apr 2015

    Observational Study

    [Chronic kidney disease in Primary Health Care: prevalence and associated risk factors].

    • Betlem Salvador González, Mercedes Rodríguez Pascual, Laura Ruipérez Guijarro, Antonia Ferré González, Oriol Cunillera Puertolas, and Luisa M Rodríguez Latre.
    • Equipo de Atención Primaria Florida Sud, Servei Atenció Primària Delta Llobregat, DAP Costa de Ponent, Institut Català de la Salut, L'Hospitalet de Llobregat, Barcelona, España; Grupo MACAP (Malaltia Cardiovascular en Atenció Primària), IDIAP Jordi Gol, Barcelona, España. Electronic address: bsalvador@ambitcp.catsalut.net.
    • Aten Primaria. 2015 Apr 1; 47 (4): 236245236-45.

    ObjectiveTo determine the prevalence of chronic kidney disease and associated risk factors in subjects over 60 years of age, as well as its staging by determining the glomerular filtration rate (GFR).DesignCross-sectional observational study.SettingPrimary Health Care.ParticipantsPatients≥60 years of age who were seen in 40 Primary Health Care centres with serum creatinine measured in a central laboratory between January 1 and December 31, 2010.Exclusion Criteriakidney transplant, home care.Main MeasuresSocial-demographic and anthropometric data, cardiovascular risk factors, and diseases established according to electronic clinical records. Serum creatinine was measured using standardised Jaffe kinetic method, and GFR estimated with MDRD-4-IDMS and CKD-EPI.ResultsA total of 97,665 subjects (57.3% women, median age 70.0 years [Q1: 65.0, Q3: 77.0]). GFR-MDRD prevalence<60=15.1% (16.6% in women, 13.2% in men; P<.001) and increased with age. Multivariate analysis showed a positive association between GFR-MDRD<60 and age (OR=1.74; 95% CI 1.70 to 1.77), hypertension (OR=2.18; 95% CI 2.08 to 2.30), heart failure (OR=2.03; 95% CI 1.83 to 2.25), atrial fibrillation (OR=1.57; 95% CI 1.41 to 1.76), ischaemic heart disease (OR=1.40; 95% CI 1.30 to 1.50), peripheral arterial disease (OR=1.31; 95% CI 1.09 to 1.57), dyslipidaemia (OR=1.28; 95% CI 1.23 to 1.33), diabetes (OR=1.26; 95% CI 1.17 to 1.34), and stroke (OR=1.17; 95% CI 1.09 to 1.25). The GFR-CKD-EPI model showed an increase in OR with age and male sex, that became significant as a chronic kidney disease risk factor.ConclusionsChronic kidney disease has considerable prevalence in subjects≥60 years seen in Primary Health Care, more in women, and increasing with age. Hypertension, more than diabetes, was the main associated cardiovascular risk factor.Copyright © 2014 Elsevier España, S.L.U. All rights reserved.

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