• Wien. Klin. Wochenschr. · Dec 2014

    [Consensus statement: Stroke prevention in nonvalvular atrial fibrillation in special consideration of the new direct oral anticoagulants].

    • Ingrid Pabinger, Wilfried Lang, Franz Xaver Roithinger, Franz Weidinger, Sabine Eichinger-Hasenauer, Reinhold Glehr, Walter-Michael Halbmayer, Hans-Peter Haring, Bernd Jilma, Hans Christian Korninger, Sibylle Kozek-Langenecker, Paul Kyrle, Herbert Watzke, Ansgar Weltermann, Johann Willeit, Kurt Huber, Österreichische Kardiologische Gesellschaft (ÖKG), Österreichische Gesellschaft für Hämatologie & Medizinische Onkologie (OeGHO), Österreichische Schlaganfall-Gesellschaft (ÖGSF), Österreichische Gesellschaft für Innere Medizin (ÖGIM), Österreichische Gesellschaft für Anästhesiologie, Reanimation und Intensivmedizin (ÖGARI), and Österreichische Gesellschaft für Allgemein- und Familienmedizin (ÖGAM).
    • Klin. Abt. für Hämatologie u. Hämostaseologie, Univ.-Klin. f. Innere Medizin I, MedUni Wien, Währinger Gürtel 18-20, 1090, Wien, Österreich, ingrid.pabinger@meduniwien.ac.at.
    • Wien. Klin. Wochenschr. 2014 Dec 1; 126 (23-24): 792-808.

    AbstractThe introduction of new direct oral anticoagulants has changed the treatment of nonvalvular atrial fibrillation. However, these changes are not yet fully reflected in current guidelines.This consensus statement, endorsed by six Austrian medical societies, provides guidance to current prophylactic approaches of thromboembolic events in nonvalvular atrial fibrillation on the basis of current evidence and published guidelines. Furthermore, some special subjects are treated, like changes in laboratory parameters and their interpretation under treatment with direct oral anticoagulants, treatment of bleedings, approach to operations, cardioversion and ablation, and specific neurological aspects. For a CHA2DS2-VASc-Score of ≥ 2, anticoagulation is recommended with a high level of evidence (1A). At the end of the consensus statement, recommendations for a number of specific patient subgroups can be found, in order to help treating physicians to arrive at appropriate therapeutic decisions.

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