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Yonsei medical journal · May 2014
ReviewAggravation of hypertriglyceridemia and acute pancreatitis in a bipolar patient treated with quetiapine.
- Li-Syue Liou, Yi-Jen Hung, Chang-Hsun Hsieh, and Fone-Ching Hsiao.
- Department of Family and Community Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
- Yonsei Med. J. 2014 May 1; 55 (3): 831-3.
AbstractPancreatitis is a very rare adverse effect of quetiapine treatment, with only 5 cases of quetiapine-associated pancreatitis reported in the English literature to date. Herein, we report one patient who developed severe hypertriglyceridemia (>1000 mg/dL) after quetiapine administration, resulting in acute pancreatitis. An analysis of the underlying pathogenic mechanisms and a review of relevant literature are also presented. Clinicians should be aware of the potentially life-threatening metabolic disturbances and/or pancreatitis associated with quetiapine therapy.
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