• James W Mold, Chester Fox, Angela Wisniewski, Paula Darby Lipman, Margot R Krauss, D Robert Harris, Cheryl Aspy, Rachel A Cohen, Kurt Elward, Paul Frame, Barbara P Yawn, Leif I Solberg, and René Gonin.
• University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
• Ann Fam Med. 2014 May 1; 12 (3): 233-40.

PurposeGuideline implementation in primary care has proven difficult. Although external assistance through performance feedback, academic detailing, practice facilitation (PF), and learning collaboratives seems to help, the best combination of interventions has not been determined.MethodsIn a cluster randomized trial, we compared the independent and combined effectiveness of PF and local learning collaboratives (LLCs), combined with performance feedback and academic detailing, with performance feedback and academic detailing alone on implementation of the National Heart, Lung and Blood Institute's Asthma Guidelines. The study was conducted in 3 primary care practice-based research networks. Medical records of patients with asthma seen during pre- and postintervention periods were abstracted to determine adherence to 6 guideline recommendations. McNemar's test and multivariate modeling were used to evaluate the impact of the interventions.ResultsAcross 43 practices, 1,016 patients met inclusion criteria. Overall, adherence to all 6 recommendations increased (P ≤.002). Examination of improvement by study arm in unadjusted analyses showed that practices in the control arm significantly improved adherence to 2 of 6 recommendations, whereas practices in the PF arm improved in 3, practices in the LLCs improved in 4, and practices in the PF + LLC arm improved in 5 of 6 recommendations. In multivariate modeling, PF practices significantly improved assessment of asthma severity (odds ratio [OR] = 2.5, 95% CI, 1.7-3.8) and assessment of asthma level of control (OR = 2.3, 95% CI, 1.5-3.5) compared with control practices. Practices assigned to LLCs did not improve significantly more than control practices for any recommendation.ConclusionsAddition of PF to performance feedback and academic detailing was helpful to practices attempting to improve adherence to asthma guidelines.

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