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- Marcello Camici, Fabio Galetta, Ferdinando Franzoni, Angelo Carpi, and Farhad Zangeneh.
- Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
- Intern Emerg Med. 2013 Apr 1; 8 Suppl 1: S5-9.
AbstractThe authors briefly review the biological effects of vitamin D on the heart and discuss the experimental and clinical studies related to the potential protective effect of vitamin D on the cardiovascular system. Experimental and observational studies in man strongly suggest that vitamin D supplementation can benefit heart failure patients and improve cardiovascular health in the population. However, presently there are limited randomized controlled studies. The authors highlight the hypothesis that vitamin D-induced mechanisms activating calcium channels may represent a novel target for therapy in patients with heart failure.
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