• Intern Emerg Med · Apr 2013

    Review

    Endothelial progenitor cells, cardiovascular risk factors and lifestyle modifications.

    • Rossella Di Stefano, Francesca Felice, Roberto Feriani, and Alberto Balbarini.
    • Dipartimento di Patologia Chirurgica, Medica, Molecolare e dell' Area Critica, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy. r.distefano@ao-pisa.toscana.it
    • Intern Emerg Med. 2013 Apr 1; 8 Suppl 1: S47-9.

    AbstractEndothelial progenitor cells (EPCs) contribute substantially to preservation of a structurally and functionally intact endothelium. EPCs home in to the sites of endothelial injury and ischemia, where they proliferate, differentiate and integrate into the endothelial layer or exert a paracrine function by producing vascular growth factors. This review will focus on successful lifestyle interventions that aim to maintain vascular health through beneficial actions on cell populations with vasculogenic potential. The results of the studies proving the role of healthy lifestyle are particularly emphasized.

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