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Internal medicine journal · Oct 2021
Subcutaneous ertapenem delivered by an Australian outpatient parenteral antimicrobial therapy service: a retrospective comparative efficacy study.
- Jonathan Hiew, Timothy Whitmore, Mahalia McEvoy, Deborah Weatherall, Paul R Ingram, and Laurens Manning.
- Multidisciplinary Diabetic Foot Ulcer Service, Fiona Stanley Hospital, Perth, Western Australia, Australia.
- Intern Med J. 2021 Oct 1; 51 (10): 1717-1721.
AbstractSubcutaneous (SC) administration of ertapenem in outpatient parenteral antimicrobial therapy (OPAT) services may be a practical alternative to intravenous delivery for complicated infections. The clinical features and outcomes according to route of administration were compared from a large Australian OPAT service. Chronic renal impairment was more common in the SC group, reflecting an opportunity for route of administration as a vein preservation strategy. Adverse events were uncommon and successful outcomes were not different between the groups.© 2021 Royal Australasian College of Physicians.
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