• Toshitake Yakushiji, Kiyoshi Oka, Hiro Sato, Shigeta Yorimitsu, Toru Fujimoto, Yasuyuki Yamashita, and Hiroshi Mizuta.
• Department of Orthopaedic and Neuro-Musculoskeletal Surgery, Kumamoto University, Kumamoto, Japan. t-yakushiji@fc.kuh.kumamoto-u.ac.jp
• J Magn Reson Imaging. 2009 Apr 1; 29 (4): 895-900.

PurposeTo detect differences in magnetic resonance imaging (MRI) between chondroblastic osteosarcoma and the other types of osteosarcomas or chondrosarcomas using gadolinium-enhanced versus diffusion-weighted sequences.Materials And MethodsContrast-enhanced MRI and diffusion-weighted imaging (DWI) were performed in five chondroblastic osteosarcoma (CO) cases, 17 other types of osteosarcomas (OS), and 18 chondrosarcomas (CS). DWI was obtained with a single-shot echo-planar imaging (EPI) sequence using a 1.5 T MR imager. The apparent diffusion coefficients (ADCs) of the minimum and maximum values were also obtained. The contrast-enhancement pattern was evaluated and minimum-maximum ADC value of CO was compared with other types of OS and CS.ResultsBoth CO and CS showed a similar enhancement pattern; both showed septonodular and peripheral rim enhancement. The minimum ADC value of CO (1.24 +/- 0.10 x 10(-3)mm(2)/sec) was significantly higher than that of other types of OS (0.84 +/- 0.15 x 10(-3)mm(2)/sec) and was significantly lower than that of CS (1.64 +/- 0.20 x 10(-3)mm(2)/sec). In addition, the maximum ADC value of CO (2.28 +/- 0.20 x 10(-3)mm(2)/sec) was significantly higher than that of other types of OS (1.33 +/- 0.26 x 10(-3)mm(2)/sec).ConclusionDWI appears to be more useful for differentiating between chondroblastic osteosarcoma and chondrosarcoma or other types of osteosarcoma than Gd-enhanced MRI.

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