• J. Korean Med. Sci. · May 2014

    Methylenetetrahydrofolate reductase 677 genotype-specific reference values for plasma homocysteine and serum folate concentrations in korean population aged 45 to 74 years: the Namwon study.

    • Sun-Seog Kweon, Young-Hoon Lee, Seul-Ki Jeong, Hae-Sung Nam, Kyeong-Soo Park, Seong-Woo Choi, Bok-Hee Kim, Hee Nam Kim, Jin-Su Choi, and Min-Ho Shin.
    • Department of Preventive Medicine, Chonnam National University Medical School and Research Institute of Medical Sciences, Gwangju, Korea. ; Vanderbilt Epidemiology Center, Institute of Medicine and Public Health, Vanderbilt University School of Medicine, Nashville, TN, USA.
    • J. Korean Med. Sci. 2014 May 1; 29 (5): 743-7.

    AbstractThe reference interval for plasma total homocysteine (tHcy) and serum folate concentrations were estimated. Total of 3,154 reference individuals (1,029 men and 2,125 women) were selected based on stringent exclusion criteria. For plasma tHcy concentration (µM/L), reference values (median [5-95 percentile]) were 7.72 (5.03 to 13.80) and 6.09 (3.95-10.19) in men and women, respectively. For serum folate concentration (nM/L), reference values were 23.71 (11.73-38.44) and 28.95 (15.23-40.44) in men and women, respectively. The tHcy levels of both genders in the present study were lower than those in previous reports from other countries and Korea.

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