• J. Korean Med. Sci. · Sep 2014

    Estimating 24-hour urine sodium level with spot urine sodium and creatinine.

    • Ho Seok Koo, Yong Chul Kim, Shin Young Ahn, Se Won Oh, Suhnggwon Kim, Ho Jun Chin, and Jung Hwan Park.
    • Department of Internal Medicine, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea.
    • J. Korean Med. Sci. 2014 Sep 1; 29 Suppl 2: S97-S102.

    AbstractThe 24-hr urine sodium excretion level was estimated based on the spot urine sodium, and the efficacy of the formula was validated to determine the status of low salt intake <100 mEq Na/day. The 24-hr urine samples were collected from 400 patients. The 24-hr urine creatinine level was estimated with the use of three formulas: a newly derived Korean equation (E24UCR_K), and Tanaka (E24UCR_T) and Cockcroft-Gault (E24UCR_CG) equations. The correlation coefficients between the estimated and measured 24-hr urine creatinine for these three equations were 0.863, 0.846, and 0.896, respectively (All P<0.001). After estimating the 24-hr urine sodium levels, the correlation coefficients between the estimated and measured 24-hr urine sodium levels were 0.466, 0.490, and 0.516, respectively (All P<0.001). The sensitivity of three formulas to estimate the measured 24-hr urine sodium≥100 mEq/day using the estimated amount≥100 mEq/day was 84.3%, 87.6%, and 84.8%, respectively. In conclusion, the three equations used to estimate the 24-hr urine sodium content were useful to determine the status of low salt intake.

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