• The lancet oncology · May 2010

    Review

    Testicular and paratesticular tumours in the prepubertal population.

    • Hashim U Ahmed, Manit Arya, Asif Muneer, Imran Mushtaq, and Neil J Sebire.
    • Division of Surgery and Interventional Sciences, University College London and UCH/UCL Comprehensive Biomedical Research Centre, London, UK. Hashim.ahmed@ucl.ac.uk
    • Lancet Oncol. 2010 May 1; 11 (5): 476-83.

    AbstractPrepubertal testicular and paratesticular tumours are a rare group of tumours, distinct from postpubertal paediatric and adult tumours of this region. Tumours within this group are testicular germ-cell tumours (such as benign teratoma, epidermoid cyst and malignant yolk-sac tumours) and stromal tumours (such as juvenile granulosa-cell, Leydig-cell, and Sertoli-cell tumours). Paratesticular tumours can be benign (lipoma, leiomyoma, haemangioma) or malignant (rhabdomyosarcoma, melanotic neuroectodermal tumour of infancy). Because of their rarity, centralised pathology and treatment, and national collaborative clinical trials have been important in establishing the optimum management of malignant tumours in this group. We provide an up-to-date and comprehensive review of the clinical presentation, imaging, pathology, and clinical management of prepubertal paratesticular and testicular tumours.2010 Elsevier Ltd. All rights reserved.

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