• Mahmood Eydi, Samad Ej Golzari, Davood Aghamohammadi, Khosro Kolahdouzan, Saeid Safari, and Zohreh Ostadi.
• Department of Anesthesiology, Tabriz University of Medical Sciences, Tabriz, Iran.
• Anesth Pain Med. 2014 May 1; 4 (2): e15499.

BackgroundOne of the unpleasant side effects of general anesthesia is shivering in the process of recovery. It is an involuntary oscillatory mechanical movement that can be classified as clonic movements. These movements can affect one or several groups of skeletal muscles beginning from 5 to 30 minutes after the discontinuation of anesthesia.ObjectivesWe aimed to study ketamine's effect on shivering after operation compared to pethidine as a way for treatment of postoperative shivering.Patients And MethodsIn this study, 60 patients who underwent ENT surgery with general anesthesia and had shivering during recovery were randomly divided into two groups of 30 patients each receiving ketamine (0.2 mg/kg IV) and pethidine (0.5 mg/kg).ResultsThere was no statistically significant difference between the shivering intensity in both groups. Only regarding the shivering in the first minute after entering the recovery room, there was an obvious difference between ketamine and pethidine groups which was again not statistically significant (P = 0.07).ConclusionsThe results of this study showed that ketamine and pethidine are both equally effective in the reduction of postoperative shivering.

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