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- M T Kilbane, M O'Keane, M Morrin, M Flynn, and M J McKenna.
- Metabolism Laboratory, St. Vincent's University Hospital, Dublin 4, Ireland, m.kilbane@svuh.ie.
- Ir J Med Sci. 2014 Sep 1; 183 (3): 485-7.
IntroductionThe Institute of Medicine (IOM) 2011 on dietary references intakes for calcium and vitamin D specified that a 25-hydroxyvitamin D (25OHD) level below 30 nmol/L indicated risk of deficiency and that a level above 125 nmol/L indicated risk of harm.MethodsWe noted a high prevalence of hypovitaminosis D (23.9 %) and a substantive prevalence of hypervitaminosis D (4.8 %) in a retrospective audit of clinical samples (n = 10,181) obtained over 10 months in 2013.ConclusionHypovitaminosis D should be corrected by low dose supplementation (5 µg or 200 IU daily) with some at-risk groups needing higher doses (10 µg or 400 IU daily) based on 25OHD levels. Whereas, those taking high-dose vitamin D supplements based on mistaken beliefs about recently authorised claims of benefit for muscle function and misleading unauthorised claims need to be alerted to the potential harms of excessive supplementation.
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