• Pak J Med Sci · Mar 2014

    Case Reports

    Systemic lupus erythematosis with severe aplastic anemia successfully treated with rituximab and antithymocyte globulin.

    • Wenbin Liu, Zhiping Hu, Shengyun Lin, Jianghua He, and Yuhong Zhou.
    • Wenbin Liu, Department of Hematology, First Clinical Medical School of Zhejiang Chinese Medicine University, China.
    • Pak J Med Sci. 2014 Mar 1; 30 (2): 449-51.

    AbstractHematologic disorders are very common in Systmic lupus erythematosus (SLE).First presentation of SLE with severe aplastic anemia (SAA) is extremely rare. We report a patient with the diagnosis of secondary SAA associated with SLE. Conventional therapy was not effective. She received Rituximab (RTX) and Antithymocyte globulin (ATG) therapy, her response was satisfactory finally. Her hematologic parameters were within normal ranges until last follow-up, eight months and six months after therapy was initiated with RTX and ATG, respectively. This is the first time RTX and ATG were successfully used in the treatment of SAA secondary to SLE.

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