• Johan G Eriksson, Samuel Sandboge, Minna K Salonen, Eero Kajantie, and Clive Osmond.
• National Institute for Health and Welfare, Department of Chronic Disease Prevention , Helsinki , Finland.
• Ann. Med. 2014 Sep 1; 46 (6): 434-8.

IntroductionObesity has reached epidemic proportions worldwide. Maternal obesity has consequences for the offspring's later health. Only few studies have focused upon the long-term consequences of maternal obesity on the offspring's later health.MethodsA total of 13,345 men and women born in Helsinki during 1934-44 belonging to the Helsinki Birth Cohort Study were included in the study. Data on maternal weight and height in late pregnancy were available from hospital records. Using validated national registers we report on the following outcomes in relation to maternal BMI: death, cancer, coronary heart disease, stroke, and diabetes among the offspring.ResultsMaternal BMI was positively associated with each of the later health outcomes of the offspring. The associations were strongest for cardiovascular disease and type 2 diabetes. The association with type 2 diabetes was stronger in women.DiscussionOur findings stress the importance of early prevention of overweight and obesity in women of child-bearing age.

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