• Nedime Sahinoglu-Keskek, Sakir Ozgur Keskek, Selim Cevher, Sinan Kirim, Asim Kayiklik, Gulay Ortoglu, and Tayyibe Saler.
• Nedime Sahinoglu-Keskek, MD, Department of Ophthalmology, Numune Training and Research Hospital, Adana, Turkey.
• Pak J Med Sci. 2014 May 1; 30 (3): 477-82.

ObjectiveThe aim of this study was to investigate the association between intraocular pressure and metabolic syndrome by comparing central corneal thicknesses.MethodsOne hundred sixty-two subjects were enrolled in this cross-sectional study, with 89 subjects in a metabolic syndrome group and 73 subjects in a control group. Ophthalmological examinations, including intraocular pressure and central corneal thickness measurements, were performed on each subject. Serum fasting glucose, triglyceride and HDL cholesterol levels were measured, and waist circumference, systolic and diastolic blood pressure of all patients were recorded.ResultsParticipants with metabolic syndrome had a significantly higher intraocular pressure than those without metabolic syndrome (p = 0.008), and there was no statistically significant difference between the central corneal thicknesses of the two groups (p = 0.553). Most of the metabolic syndrome components were associated with higher intraocular pressure (p < 0.05).ConclusionsThere is a relationship between metabolic syndrome and intraocular pressure, but no association between metabolic syndrome and central corneal thicknesses. Intraocular pressure is affected by central corneal thicknesses, and intraocular pressure is used to correct according to the central corneal thicknesses measurement. To our knowledge, this is the first study that determines the positive relationship between metabolic syndrome and intraocular pressure by comparing the central corneal thicknesses of the groups.

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