• J Dtsch Dermatol Ges · Feb 2009

    Case Reports

    Treatment of severe recalcitrant hidradenitis suppurativa with adalimumab.

    • Viola Harde and Ulrich Mrowietz.
    • Department of Dermatology, Allergy and Venereology, University Clinic Schleswig-Holstein, Campus Kiel, Schittenhelmstrasse 7, Kiel, Germany. vharde@dermatology.uni-kiel.de
    • J Dtsch Dermatol Ges. 2009 Feb 1; 7 (2): 139-41.

    AbstractHidradenitis suppurativa is a chronic inflammatory skin disease featuring inflammatory nodules, fistulas and discharge of secretions in the intertriginous regions. Without therapy the disease is chronic and progressive. The most effective treatment is the radical wide excision of the affected areas. Systemic antibiotics, immunosuppressants, oral retinoids or antiandrogens have limited beneficial effects. TNF-alpha antagonists may represent a new therapeutic approach for patients suffering from severe hidradenitis suppurativa offering promising positive influence on the disease outcome. In contrast to infliximab and etanercept, there are only few reports describing the use of adalimumab in severe hidradenitis suppurativa. Here we report a case of a patient with severe recalcitrant hidradenitis suppurativa successfully treated with adalimumab.

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