• Orthop. Clin. North Am. · Jan 2016

    Review

    Innovations in Intraoperative Tumor Visualization.

    • Julia D Visgauss, William C Eward, and Brian E Brigman.
    • Department of Orthopaedic Surgery, Duke University, Box 3312 DUMC, Durham, NC 27710, USA.
    • Orthop. Clin. North Am. 2016 Jan 1; 47 (1): 253-64.

    AbstractIn the surgical management of solid tumors, adequacy of tumor resection has implications for local recurrence and survival. The standard method of intraoperative identification of tumor margin is frozen section pathologic analysis, which is time-consuming with potential for sampling error. Intraoperative tumor visualization has the potential to significantly improve surgical cancer care across disciplines, by guiding accuracy of biopsies, increasing adequacy of resections, directing adjuvant therapy, and even providing diagnostic information. We provide an outline of various methods of intraoperative tumor visualization developed to aid in the real-time assessment of tumor extent and adequacy of resection. Copyright © 2016 Elsevier Inc. All rights reserved.

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