• J Thorac Dis · Dec 2013

    Review

    Management strategy of solitary pulmonary nodules.

    • Ping Zhan, Haiyan Xie, Chunhua Xu, Keke Hao, Zhibo Hou, and Yong Song.
    • Department of Respiratory Medicine, Nanjing Chest Hospital, Nanjing 210029, China; ; Nanjing Clinical Center of Respiratory Diseases, Nanjing 210029, China;
    • J Thorac Dis. 2013 Dec 1;5(6):824-9.

    AbstractSolitary pulmonary nodules (SPNs) are increasingly detected with the widespread use of chest computed tomography (CT) scans. The management of patients with SPN should begin with estimating the probability of cancer from the patient's clinical risk factors and CT characteristics. The decision-making process need to incorporate the probability of cancer, the potential benefits and harms of surgery, the accuracy of the available diagnostic tests and patient preferences. For patients with a very low probability of cancer, careful observation with serial CT is warranted. For patients in the intermediate range of probabilities, either CT-guided fine-needle aspiration biopsy (FNAB) or positron emission tomography (PET), is recommended. For those with a high probability of cancer, surgical diagnosis is warranted.

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