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Mem. Inst. Oswaldo Cruz · Jan 2020
Identification of SARS-CoV-2 and additional respiratory pathogens cases under the investigation of COVID-19 initial phase in a Brazilian reference laboratory.
- Aline da Rocha Matos, Fernando Couto Motta, Braulia Costa Caetano, Maria Ogrzewalska, Cristiana Couto Garcia, Jonathan Christian Oliveira Lopes, Milene Miranda, Miriam Teresinha Furlam Prando Livorati, André Abreu, David Brown, and Marilda Mendonça Siqueira.
- Fundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Vírus Respiratórios e do Sarampo, Rio de Janeiro, RJ, Brasil.
- Mem. Inst. Oswaldo Cruz. 2020 Jan 1; 115: e200232.
AbstractCoronavirus disease 2019 (COVID-19) surveillance, in Brazil, initiated shortly after its description, in China. Our aim was to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and additional pathogens in samples from the initial phase of the outbreak in Brazil, from late February to late March. From 707 samples analysed, 29 (4.1%) were SARS-CoV-2 positive. Fever and cough were their most prevalent symptoms. Co-detection of rhinovirus was observed in 2 (6.9%) cases. Additional pathogens were identified in 66.1% of the SARS-CoV-2 negative cases, mainly rhinovirus and influenza A(H1N1)pdm09. Thus, we emphasise the importance of differential diagnosis in COVID-19 suspected cases.
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