• Younghoon Kwon, Patrick L Stafford, Kyle Enfield, Sula Mazimba, and Martin C Baruch.
• Department of Medicine, University of Washington, Seattle, WA. Electronic address: yhkwon@uw.edu.
• J. Cardiothorac. Vasc. Anesth. 2022 Jul 1; 36 (7): 201220212012-2021.

ObjectiveTo examine the accuracy of noninvasively-derived peripheral arterial blood pressure (BP) by the Caretaker device (CT) against invasively measured arterial BP and the fidelity of heart rate variability by CT compared with electrocardiogram (ECG)-derived data.DesignProspective cohort study.ParticipantsAdult surgical and trauma patients admitted to the intensive care unit.SettingAcademic tertiary care medical center.InterventionsIn a prospective manner, beat-by-beat BP by CT was recorded simultaneously with invasive arterial BP measured in patients in the intensive care unit. Invasive arterial BPs were compared with those obtained by the CT system. All comparisons among the CT data, arterial catheter data, and ECG data were postprocessed.Measurements And Main ResultsFrom 37 enrolled patients, 34 were included with satisfactory data that overlapped between arterial catheter and CT. A total of 87,757 comparative data points were obtained for the 40-minute time window comparisons of the 34 patients, spanning approximately 22.5 hours in total. Systolic BP and diastolic BP correlations (Pearson coefficient), as well as the mean difference (standard deviation), were 0.92 and -0.36 (7.57) mmHg and 0.83 and -2.11 (6.00) mmHg, respectively. The overall interbeat correlation was 0.99, with the mean difference between interbeats obtained with the arterial BP and the CT of -0.056 ms (6.0).ConclusionsThis study validated the noninvasive tracking of BP using the CT device, and the pulse decomposition analysis approach is possible within the guidelines of the standard.Copyright © 2021 Elsevier Inc. All rights reserved.

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