• Isr Med Assoc J · Oct 2021

    Case Reports

    Candida Bloodstream Infection, a Dire Complication in Hospitalized COVID-19 Patients: Three Cases from a Single Center in Northern Israel.

    • Shay Brikman, Guy Dori, Carmel Kasher, Anna Yanovskay, Merav Strauss, Raul Colodner, Naiel Bisharat, and Bibiana Chazan.
    • Internal Medicine Ward E, Emek Medical Center, Afula, Israel.
    • Isr Med Assoc J. 2021 Oct 1; 23 (10): 615-617.

    BackgroundPatients with severe coronavirus disease-2019 (COVID-19) are susceptible to superimposed infections.ObjectivesTo describe COVID-19 patients who presented with complications due to Candida bloodstream co-infection (candidemia) and their outcome in a single center in northern Israel (Emek Medical Center) during the second outbreak of COVID-19 in Israel (15 June 2020 to 20 September 2020).MethodsA retrospective study of COVID-19 patients presenting with candidemia was conducted, including clinical and laboratory data. The incidence of candidemia among hospitalized COVID-19 patients was compared to a historical cohort of non-COVID-19 controls.ResultsThree COVID-19 patients complicated with candidemia were documented. All three patients died shortly after the detection of candidemia. Three different Candida sp. were isolated from the blood cultures: C. albicans, C. parapsilosis, and C. glabrata. The incidence of candidemia among COVID-19 patients was 0.679 episodes per 1000 hospital days.ConclusionsOur small sample suggests a much higher incidence of candidemia among COVID-19 patients compared to a historical cohort of non-COVID-19 controls. All clinicians treating COVID-19 patients in GICU should be aware of this complication.

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