• Best Pract Res Clin Rheumatol · Dec 2015

    Review

    Inflammatory myopathies and overlap syndromes: Update on histological and serological profile.

    • Serena Colafrancesco, Roberta Priori, and Guido Valesini.
    • Dipartimento di Medicina Interna e Specialita' Mediche, UOC Reumatologia, SapienzaUniversita' di Roma, Italy. Electronic address: serena.colafrancesco18@gmail.com.
    • Best Pract Res Clin Rheumatol. 2015 Dec 1; 29 (6): 810-25.

    AbstractThe term 'inflammatory myopathies' (IMs) comprise a group of muscle diseases formed by four main categories known as polymyositis (PM), dermatomyositis (DM), inclusion body myositis (IBM) and immune-mediated necrotizing myopathy (IMNM). Due to the increasing evidence of IMs over the course of different autoimmune diseases, the overlap myositis (OM) has been recently recognized as a possible stand-alone entity. IMs are characterized by a wide spectrum of autoantibodies, and the panel of myositis-associated autoantibodies (MAA) has dramatically increased over the last years giving the clinicians a further crucial support to differentiate the different types of myositis. This study aims to collect the most relevant evidence published up to date on the most commonly described OM with a particular emphasis on their histological aspects and also serological features.Copyright © 2016 Elsevier Ltd. All rights reserved.

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