• Mustafa Tarık Ağaç, Levent Korkmaz, Hüseyin Bektas, Zeydin Acar, Hakan Erkan, Ibrahim Halil Kurt, Adem Adar, and Sükrü Celik.
• Department of Cardiology, Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital, Trabzon, Turkey.
• Med Princ Pract. 2014 Jan 1; 23 (1): 66-9.

ObjectiveTo investigate the presence of myocardial fibrosis determined by fragmented QRS in patients with severe aortic valve stenosis.Subjects And MethodsEighty-seven consecutive patients with severe aortic valve stenosis and 83 age- and gender-matched control subjects were enrolled into this study. Severe aortic valve stenosis was defined as an aortic valve area <1 cm(2), a Vmax >4 m/s, or a mean gradient ≥40 mm Hg. Fragmented QRS was assessed using a 12-lead electrocardiogram.ResultsFragmented QRS was detected in 40 (46%) patients in the aortic valve stenosis group and in 15 (18%) control subjects (p < 0.001). In multivariate binary logistic regression analysis, the presence of aortic valve stenosis was the only independent factor associated with fragmented QRS (OR = 3.69; 95% CI 1.81-7.55, p < 0.001).ConclusionA higher frequency of fragmented QRS was detected in patients with severe aortic valve stenosis compared to controls.© 2013 S. Karger AG, Basel.

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