• Cochrane Db Syst Rev · Oct 2014

    Review

    Prophylactic antibiotics for manual removal of retained placenta in vaginal birth.

    • Chompilas Chongsomchai, Pisake Lumbiganon, and Malinee Laopaiboon.
    • Department of Obstetrics and Gynaecology, Faculty of Medicine, Khon Kaen University, Mittraphab Road, Khon Kaen, Thailand, 40002.
    • Cochrane Db Syst Rev. 2014 Oct 20; 2014 (10): CD004904CD004904.

    BackgroundRetained placenta is a potentially life-threatening condition because of its association with postpartum hemorrhage. Manual removal of placenta increases the likelihood of bacterial contamination in the uterine cavity.ObjectivesTo compare the effectiveness and side-effects of routine antibiotic use for manual removal of placenta in vaginal birth in women who received antibiotic prophylaxis and those who did not and to identify the appropriate regimen of antibiotic prophylaxis for this procedure.Search MethodsWe searched the Cochrane Pregnancy and Childbirth Group's Trials Register (31 July 2014).Selection CriteriaAll randomized controlled trials comparing antibiotic prophylaxis and placebo or non antibiotic use to prevent endometritis after manual removal of placenta in vaginal birth.Data Collection And AnalysisThere are no included trials. In future updates, if we identify eligible trials, two review authors will independently assess trial quality and extract dataMain ResultsNo studies that met the inclusion criteria were identified.Authors' ConclusionsThere are no randomized controlled trials to evaluate the effectiveness of antibiotic prophylaxis to prevent endometritis after manual removal of placenta in vaginal birth.

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