• Neuroimaging Clin. N. Am. · Nov 2021

    Review

    Imaging of Acute and Chronic Skull Base Infection.

    • Sriram Vaidyanathan and Ravi Kumar Lingam.
    • Department of Radiology and Nuclear Medicine, St James's University Hospital, Leeds Teaching Hospitals NHS Trust, Beckett Street, Leeds LS9 7TF, UK. Electronic address: svaidyanathan@nhs.net.
    • Neuroimaging Clin. N. Am. 2021 Nov 1; 31 (4): 571-598.

    AbstractSkull base infections are uncommon but can be life threatening without timely recognition. Imaging plays a crucial role because symptoms can be vague and nonlocalizing. Necrotizing otitis externa in diabetic or immunocompromised patients is the commonest cause of skull base osteomyelitis (SBO), followed by sinogenic infections and idiopathic central SBO. Multiparametric magnetic resonance (MR) and high-resolution CT are the mainstays for establishing a diagnosis and estimating disease extent, with MR being superior in ascertaining marrow and soft tissue involvement. Monitoring treatment response, of which imaging is a fundamental part, is challenging, with emerging promising imaging tools.Copyright © 2021 Elsevier Inc. All rights reserved.

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