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Annals of neurology · Sep 2019
High-resolution diffusion-weighted imaging identifies ischemic lesions in a majority of transient ischemic attack patients.
- Benjamin Hotter, Ivana Galinovic, Claudia Kunze, Peter Brunecker, Gerhard J Jungehulsing, Arno Villringer, Matthias Endres, Kersten Villringer, and Jochen B Fiebach.
- Center for Stroke Research Berlin, Charité Universitätsmedizin Berlin, Berlin, Germany.
- Ann. Neurol. 2019 Sep 1; 86 (3): 452-457.
AbstractTransient ischemic attack (TIA) is defined as focal neurological deficit caused by ischemia resolving within 24 hours. In a secondary analysis of a large monocentric cohort of 446 TIA patients, we explored the frequency and determinants of diffusion-weighted imaging (DWI) lesions on high-resolution magnetic resonance imaging. Overall, 240 (54%) of all TIA patients presented with DWI lesions. These patients had higher National Institute of Health Stroke Scale and ABCD2 scores and presented more frequently with vessel occlusion and perfusion deficits, but had similar functional outcome at 3 months. Taken together, high-resolution DWI provides evidence of ischemic brain injury in the majority of TIA patients. ANN NEUROL 2019;86:452-457.© 2019 The Authors. Annals of Neurology published by Wiley Periodicals, Inc. on behalf of American Neurological Association.
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