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Journal of hepatology · May 2017
EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure.
- European Association for the Study of the Liver. Electronic address: easloffice@easloffice.eu, Clinical practice guidelines panel, Julia Wendon,, Panel members, Juan Cordoba, Anil Dhawan, Fin Stolze Larsen, Michael Manns, Didier Samuel, Kenneth J Simpson, Ilan Yaron, EASL Governing Board representative, and Mauro Bernardi.
- J. Hepatol. 2017 May 1; 66 (5): 1047-1081.
AbstractThe term acute liver failure (ALF) is frequently applied as a generic expression to describe patients presenting with or developing an acute episode of liver dysfunction. In the context of hepatological practice, however, ALF refers to a highly specific and rare syndrome, characterised by an acute abnormality of liver blood tests in an individual without underlying chronic liver disease. The disease process is associated with development of a coagulopathy of liver aetiology, and clinically apparent altered level of consciousness due to hepatic encephalopathy. Several important measures are immediately necessary when the patient presents for medical attention. These, as well as additional clinical procedures will be the subject of these clinical practice guidelines.Copyright © 2016 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
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