• Med. Clin. North Am. · Nov 2021

    Review

    What to Do with Incidentally Discovered Pituitary Abnormalities?

    • Fabienne Langlois and Maria Fleseriu.
    • Division of Endocrinology, Department of Medicine, Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada.
    • Med. Clin. North Am. 2021 Nov 1; 105 (6): 1081-1098.

    AbstractPituitary incidentalomas are discovered in approximately 10% to 40% of brain images. A complete patient history, physical examination, and dedicated pituitary function testing are needed, and subsequent results should lead to appropriate patient management. However, most lesions are asymptomatic pituitary adenomas or Rathke cleft cysts with a benign course. Many lesions can be clinically significant, including prolactinomas or other pituitary adenomas that warrant specific pituitary disease treatment. In other cases, mass effect causing visual compromise or refractory headache indicates a need for surgery. Here, various facets of a complex evaluation and treatment algorithm for pituitary incidentalomas are reviewed.Crown Copyright © 2021. Published by Elsevier Inc. All rights reserved.

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