• Xiaojing Liu, Kun Yuan, Xuekui Ye, and Rui Liu.
• Department of Gynecology, The Fourth Hospital of Shijiazhuang, Shijiazhuang, China.
• Ir J Med Sci. 2022 Oct 1; 191 (5): 2019-2027.

BackgroundReminiscence therapy (RT) relieves mental disorders and improves quality of life (QoL) in some cancer survivors, but in postoperative cervical cancer patients, its effect is unclear. This study aimed to assess the impact of reminiscence therapy involved care (RTIC) and usual care (UC) on anxiety, depression, QoL, and survival in postoperative cervical cancer patients.MethodsIn this randomized control study, 152 eligible postoperative cervical cancer patients were randomized as 1:1 ratio into RTIC (N = 76) and UC (N = 76) groups: the former received routine care and RT, while the latter only received routine care for 12 months. Anxiety, depression, and QoL were evaluated from baseline (month (M) 0) to M12, respectively. Patients were continuously followed up to M36 for overall survival (OS) calculation.ResultsHADS-Anxiety score from M6 to M12 was decreased; both HADS-Depression score from M9 to M12 and depression rate at M12 were reduced in RTIC group compared with UC group (all P < 0.05). QLQ-C30 global health status score at M6 and M12, as well as QLQ-C30 function score at M12, was increased in RTIC group compared with UC group (all P < 0.05). However, QLQ-C30 symptom score at each visit and OS exhibited no difference between the two groups. From sub-group analysis, RTIC disclosed a distinct effect on patients whose age ≥ 50 years but not on those < 50 years.ConclusionRTIC reduces anxiety (partly) and depression and improves QoL in postoperative cervical cancer patients, especially in old patients.© 2021. Royal Academy of Medicine in Ireland.

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