• Internal medicine · May 2022

    Case Reports

    Rhabdomyolysis Caused by Gefitinib Overdose: A Case Report.

    • Shohei Obayashi, Katsuyoshi Tomomatsu, Mika Urata, Jun Tanaka, Kyoko Niimi, Naoki Hayama, Tsuyoshi Oguma, Koichiro Asano, and Yoko Ito.
    • Division of Pulmonary Medicine, Department of Medicine, Tokai University School of Medicine, Japan.
    • Intern. Med. 2022 May 15; 61 (10): 1577-1580.

    AbstractEpidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are common therapeutic agents for EGFR mutation-positive advanced non-small-cell lung cancer. There has been no report of rhabdomyolysis caused by an overdose of EGFR-TKIs. We herein review the existing literature on the subject and report a rare case of rhabdomyolysis due to an overdose of gefitinib, an EGFR-TKI.

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