• Internal medicine · Jan 2021

    Case Reports

    Tracheobronchopathia Osteochondroplastica Associated with Fibrotic Interstitial Lung Disease.

    • Jung Won Heo, Eung Gu Lee, Bomi Gil, Hye Seon Kang, and Yong Hyun Kim.
    • Department of Internal Medicine, Chung-Ang University H.C.S Hyundae Hospital, Republic of Korea.
    • Intern. Med. 2021 Jan 1; 60 (21): 3463-3467.

    AbstractTracheobronchopathia osteochondroplastica (TPO) is a very rare, benign disorder involving the lumen of the trachea-bronchial tree. However, its etiology is unknown. In our first case, observation for several years showed that TPO worsened as interstitial lung disease was aggravated. In the second case, the lung parenchymal lesion on computed tomography (CT) was found to be compatible with interstitial lung abnormality (ILA). We believe that our cases suggest a common pathogenetic relationship between TPO and fibrotic interstitial lung disease. TGF-β is likely a common factor in the pathogenesis of TPO and fibrotic interstitial lung disease.

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