• Bruno Sergi, Mario Balducci, Gaetano Paludetti, Alessandro Olivi, Pasqualina Maria Picciotti, Eugenio De Corso, Giulio Cesare Passali, Anna Rita Fetoni, and Daniela Lucidi.
• Head & Neck Department, Università Cattolica del Sacro Cuore, Rome, Italy; Otorhinolaryngology and Head & Neck Surgery Unit, Fondazione Policlinico Universitario "A. Gemelli"-IRCCS, Rome, Italy.
• World Neurosurg. 2022 Jan 1; 157: e506-e513.

BackgroundManagement of vestibular schwannoma (VS) is a complex process aimed at identifying a clinical indication for fractionated stereotactic radiotherapy (sRT) or radiosurgery, microsurgical resection, or wait and scan (WS). We describe the experience of our VS multidisciplinary team (MDT) at a tertiary university referral center created for diagnosis, treatment, and follow-up of VS patients.MethodsWe conducted a retrospective study on 132 consecutive patients referred to the MDT and managed by observation (WS), microsurgery, or fractionated sRT. The analysis included patient age, tumor size, hearing level, facial nerve function, tumor control, complications, and quality of life questionnaires.ResultsAmong the patients, 21% were subjected to microsurgery, 10% to sRT, and 69% to WS. The median follow-up time was 30 months. Outcomes based on different management modalities are described. Statistically significant differences among groups were detected in terms of quality of life (physical domain).ConclusionsMDT may provide the best individualized therapy for VS patients compared with a single gold-standard strategy.Copyright © 2021 Elsevier Inc. All rights reserved.

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