• Med. Clin. North Am. · Jan 2015

    Review

    Polycystic ovarian syndrome.

    • Subbulaxmi Trikudanathan.
    • Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington Medical Center, 4245 Roosevelt Way Northeast, Seattle, WA 98105, USA. Electronic address: tsubbu@uw.edu.
    • Med. Clin. North Am. 2015 Jan 1; 99 (1): 221-35.

    AbstractWomen with PCOS present with signs of chronic anovulation, hyperandrogenism, and metabolic abnormalities. The NIH recently embraced the Rotterdam criteria to broadly identify all the phenotypes of PCOS. Women with PCOS are often obese with insulin resistance and hence have an increased susceptibility to glucose intolerance and type 2 diabetes. Future research should focus on the genetic, epigenetic, and environmental determinants of PCOS to develop new therapies to address the prevention of this disorder and its long-term complications.Copyright © 2015 Elsevier Inc. All rights reserved.

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