• Woo Jin Joo, Kazuki Ide, Kei Nishiyama, Tomotsugu Seki, Hiroyuki Tanaka, Jumpei Tsuchiya, Noritoshi Ito, Kosuke Yoshida, and Koji Kawakami.
• Department of Pharmacoepidemiology Graduate School of Medicine and Public Health Kyoto University Kyoto Japan.
• Acute Med Surg. 2020 Jan 1; 7 (1): e491.

AimTo investigate the association between regional cerebral oxygen saturation (rSO2) and neurological outcomes in extracorporeal cardiopulmonary resuscitation (ECPR) patients after out-of-hospital cardiac arrest (OHCA).MethodsWe used data from the Japan-Prediction of Neurological Outcomes in Patients Post-Cardiac Arrest Registry. This registry included consecutive comatose patients after OHCA who were transferred to 15 hospitals in Japan from 2011 to 2013. Our primary end-point was a good neurological outcome (cerebral performance categories 1 or 2) at 90 days after OHCA.ResultsAmong the enrolled patients, 121 (6.3%) received ECPR. Eleven (9.1%) had a good neurological outcome. Receiver operating characteristic curve analysis revealed the optimal cut-off value as >16%. Good neurological outcomes were observed in 19.6% (9/46) and 2.7% (2/74) of patients with rSO2 >16% and rSO2 ≤16%, respectively.ConclusionThe neurological outcome of ECPR patients differed according to their rSO2 values. When considering ECPR, the rSO2 value could be important in addition to other criteria. Further studies that focus on ECPR patients and serial rSO2 values are needed.© 2020 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine.

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