• Yuyu Jiang, Fenglan Liu, Jianlan Guo, Pingping Sun, Zhongyi Chen, Jinping Li, Liming Cai, Hongqing Zhao, Ping Gao, Zhaosheng Ding, and Xiaoliang Wu.
• Research Office of Chronic Disease Management and Rehabilitation, Wuxi School of Medicine, Jiangnan University, Wuxi, China.
• J. Med. Internet Res. 2020 Apr 21; 22 (4): e17089.

BackgroundThe application of telemedicine in home pulmonary rehabilitation interventions for the management of patients with chronic obstructive pulmonary disease (COPD) has achieved promising results.ObjectiveThis study aimed to develop a WeChat official account (Pulmonary Internet Explorer Rehabilitation [PeR]) based on social media. It further evaluated the effect of PeR on the quality of life, symptoms, and exercise self-efficacy of patients with COPD.MethodsThe functional modules of PeR were developed by a multidisciplinary team according to the electronic health-enhanced chronic care model (eCCM) components. A total of 106 patients were randomly selected (53 in the PeR group and 53 in the outpatient face-to-face group [FtF]). Pulmonary rehabilitation intervention was conducted for 3 months, and the outcome was observed for 3 months. The primary outcome was patient quality of life measured with the COPD assessment test (CAT). The secondary outcomes were evaluated using the modified Medical Research Council scale (mMRC), exercise self-regulatory efficacy scale (Ex-SRES), and St George's Respiratory Questionnaire (SGRQ).ResultsThe intention-to-treat analysis was used in the study. A total of 94 participants completed the 6-month pulmonary rehabilitation program. No statistically significant differences were observed in CAT (F1,3=7.78, P=.001), Ex-SRES (F1,3=21.91, P<.001), and mMRC scores (F1,3=29.64, P<.001) between the two groups with the variation in time tendency. The Ex-SRES score had a significant effect on the CAT score (P=.03). The partial regression coefficient of Ex-SRES to CAT was 0.81, and Exp (B) was 2.24.ConclusionsThe telemedicine technology was effective using the eCCM combined with a behavioral intervention strategy centering on self-efficacy. Pulmonary rehabilitation at home through PeR and FtF could improve the sense of self-efficacy and quality of life and alleviate symptoms in patients with COPD.Trial RegistrationChinese Clinical Trial Registry ChiCTR1900022770; https://tinyurl.com/tmmvpq3.©Yuyu Jiang, Fenglan Liu, Jianlan Guo, Pingping Sun, Zhongyi Chen, Jinping Li, Liming Cai, Hongqing Zhao, Ping Gao, Zhaosheng Ding, Xiaoliang Wu. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 21.04.2020.

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