• J. Pediatr. Hematol. Oncol. · Nov 2008

    Case Reports

    Dyshemoglobinemias and pulse oximetry: a therapeutic challenge.

    • Anne Hladik and Kecha Lynshue.
    • Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA. ajhladik@texaschildrens.org
    • J. Pediatr. Hematol. Oncol. 2008 Nov 1; 30 (11): 850-2.

    AbstractPulse oximetry normally provides a reliable indicator of arterial blood oxygen saturation. Individuals with a variant hemoglobin with low oxygen affinity would exhibit pulse oximetry values consistent with hypoxemia despite maintaining adequate oxygen delivery to tissues. We describe a patient we diagnosed with hemoglobin Rothschild and his mother. He presented with SpO2 81% on pulse oximetry and PaO2 on arterial blood gas of 47 mm Hg, while his mother had SpO2 87%. These values were significantly lower than physical examination suggested. A possible dyshemoglobinemia should be suspected when discordance exists between pulse oximetry readings and physical examination findings.

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