• Jin-Seok Park, Don Haeng Lee, Jun Hyeok Lim, Seok Jeong, and Young Sun Jeon.
• Jin-Seok Park, Don Haeng Lee, Jun Hyeok Lim, Seok Jeong, Department of Internal Medicine, Digestive Disease Center, Inha University School of Medicine, Incheon 400-711, South Korea.
• World J. Gastroenterol. 2015 Jan 7; 21 (1): 276-82.

AimTo determine the risk factors for gallstone-related biliary events.MethodsThis retrospective cohort study evaluated magnetic resonance cholangiopancreatography images from 141 symptomatic and 39 asymptomatic gallstone patients who presented at a single tertiary hospital between January 2005 and December 2012.ResultsLogistic regression analysis showed significant differences between symptomatic and asymptomatic patients with gallstones in relation to the number of gallstones, the angle between the long axis of the gallbladder and the cystic duct, and the cystic duct diameter. Multivariate analysis showed that the number of gallstones (OR = 1.27, 95%CI: 1.03-1.57; P = 0.026), the angle between the long axis of the gallbladder and the cystic duct (OR = 1.02, 95%CI: 1.00-1.03; P = 0.015), and the diameter of the cystic duct (OR = 0.819, 95%CI: 0.69-0.97; P = 0.018) were significantly associated with biliary events. The incidence of biliary events was significantly elevated in patients who had the presence of more than two gallstones, an angle of > 92° between the gallbladder and the cystic duct, and a cystic duct diameter < 6 mm.ConclusionThese findings will help guide the treatment of patients with asymptomatic gallstones. Clinicians should closely monitor patients with asymptomatic gallstones who exhibit these characteristics.

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