• Internal medicine · Jan 2022

    Case Reports

    Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19: A Case Report.

    • Norihito Omote, Yoshihiro Kanemitsu, Takahiro Inoue, Toshiyuki Yonezawa, Takuji Ichihashi, Yuichiro Shindo, Koji Sakamoto, Akira Ando, Atsushi Suzuki, Akio Niimi, Satoru Ito, Kazuyoshi Imaizumi, and Naozumi Hashimoto.
    • Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Japan.
    • Intern. Med. 2022 Jan 15; 61 (2): 233-236.

    AbstractWe herein report a case of acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) triggered by COVID-19. An 87-year-old woman tested positive for COVID-19 on a polymerase chain reaction test, and computed tomography revealed ground-glass opacity (GGO) superimposed on a background pattern consistent with usual interstitial pneumonia. Considering these data, we diagnosed her with AE-IPF. She experienced worsening of dyspnea and expansion of the GGO. Therefore, we introduced high-dose steroids (methylprednisolone 250 mg/day for 3 days). After the treatment, the pulmonary infiltrates improved. She was discharged from our hospital without severe disability. High-dose steroids can be a viable treatment option for AE-IPF triggered by COVID-19.

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